عنوان مقاله [English]
Infections caused by vancomycin resistant enterococci (VRE) is increasing all over the world Ast.mqavmt glycopeptide antibiotics the bacteria associated with genes van A, B, C, D, E is the effect of the antibiotics in the wall of the bacteria. Most cases of VRE are Enterococcus Fyshyvm inherently resistant to tobramycin gentamicin so as aminoglycoside of choice for combination therapy with bactericidal agents used Recently it was reported that many VRE very high resistance to all aminoglycosides and even gentamicin shows. With the development of resistant strains of enterococci, so this research is to find new antimicrobial agents against vancomycin resistant enterococci is done.
After sampling the soil and surrounding villages Qom, isolation and identification of Streptomyces strains on the environment was ISP4 After separation and purification, isolates were vancomycin resistant enterococci in vitro against MHA, BHI, Hicky trenser medium was granted a total of 125 isolates, 5 isolates growth inhibitory activity against VRE showed. Strain that most halo of inhibition against enterococcal isolates showed biochemical and morphological traits and 16s rRNA sequences were identified based on identification results showed that superior strains similar to the 100% of the Bashd.nalyz Streptomyses tendae ATTC 19812 GC-Mass. after extraction with ethyl acetate, the active ingredient of the culture medium showed that the active...